Marya Cartridge Filling and Sealing System for Prefilled Biotech Products

Customization: Available
After-sales Service: Engineers Available to Service Machinery Overseas, Free Spare Parts, Online Support,video Technical Support
Certification: CE, FDA, GMP, ISO

Product Description

Basic Information
Model NO.
AE
Condition
New
Filling Principle
Peristaltic Pump Filling
Machine Type
Syringe Filling Machine
Main Material
Stainless Steel
Filling Accuracy
99%
Warranty
1 Year
High Precision
Ceramic Plunger Pump
Packaging & Delivery
Package Size
200.00cm * 150.00cm * 100.00cm
Gross Weight
100.000kg
Filling and Sealing System

Cartridge Filling and Sealing System for Prefilled Biotech Products

The pre-filled syringe filling and stoppering production line is used for the sterile filling of RTU pre-filled syringe, RTU vial, RTU cartridge, etc. It can automatically complete unpacking, filling, stoppering and other process steps, widely used in pharmaceutical, cosmetic medicine, and medical industries.

Equipment Detail 1
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It can accurately fill small doses of drugs, such as vaccines and biological products, antithrombotic drugs, and cosmetic medicine products. The system effectively isolates the equipment from the external environment to prevent drug pollution and improve production efficiency.

Performance Features
  • High precision: High-precision ceramic plunger pump accurately controls filling volume.
  • Efficiency: Covers capacity needs from low to high speed production.
  • Sterile operation: Maintains a sterile environment to prevent microbial contamination.
  • Intelligent control: Automatic monitoring and adjustment via user-friendly interface.
  • Regulatory conformance: Meets GMP, FDA 21CFR part 11 and other regulatory requirements.
  • Modular design: Applicable to various sizes of packaging materials by replacing parts.
  • Safety: Equipped with stopper missing detection and various alarm systems.
Process View 1
Process View 2
Optional Configuration:

1. Nitrogen filling system for antioxidant requirements.
2. Vacuum filling and stoppering mode for various rubber stoppers.
3. Expandable laminar flow for Class A clean environment protection.
4. Online PMS monitoring system for real-time sterility data traceability.
5. Online sterilization plunger pump for CIP/SIP capability.

Key Features Summary
Feature Details
ApplicationSterile filling of RTU syringes, vials, and cartridges.
PrecisionHigh-precision ceramic plunger pump ensures accurate dosage.
EfficiencySupports medium-low, medium-high, and high-speed production.
SterilityMaintains sterile environment during filling and stoppering.
Filling SystemsCeramic pumps, peristaltic pumps, and time-pressure methods.
Production ModesSupports batch and continuous production.
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Frequently Asked Questions (FAQ)
Q1: What types of RTU containers can this system handle?
The system is designed for the sterile filling of RTU (Ready-to-Use) pre-filled syringes, RTU vials, and RTU cartridges.
Q2: How accurate is the filling process?
The machine utilizes high-precision ceramic plunger pumps and servo motor controls to achieve a filling accuracy of approximately 99%.
Q3: Does the equipment support sterile manufacturing environments?
Yes, the equipment is designed to maintain a sterile environment during filling and stoppering, and can be integrated with Class A laminar flow protection and isolators.
Q4: Can the machine be integrated with CIP/SIP systems?
Clean-in-Place (CIP) and Sterilization-in-Place (SIP) systems are available as optional configurations for the filling systems.
Q5: Is it compliant with international pharmaceutical regulations?
Yes, the production line meets GMP, FDA 21CFR part 11, and other major regulatory requirements for pharmaceutical production.
Q6: What filling systems are available for different liquid characteristics?
We offer various filling systems including ceramic plunger pumps, peristaltic pumps, metal plunger pumps, and time-pressure methods, which can be configured independently or combined.

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